VSV-GFP treatment resulted in slight increases in secreted IFNβ in H838 and H2009 cells (p < 0.05), but no statistically significant increase in the other cell lines was observed compared to untreated control cells (Figure 1G) demonstrating that most NSCLC cells have defects in IFNβ production upon viral infection as has been previously shown [9]. This evidence concerns the gene IFNB1 and viral infectious disease.