To determine whether KLF4 also synergizes with BLIMP1 to induce lytic reactivation in latently infected EBV-positive epithelial cell lines, we transfected KLF4 and BLIMP1 expression vectors (alone or in combination) into HONE-Akata, NOKs-Akata or SNU.719 cells (an EBV-positive gastric carcinoma line). Here, PRDM1 is linked to gastric carcinoma.