With regard to evaluation of tumor proliferation in the nude mice, typically large tumor nodules on the peritoneum, as well as an abundant tumor spread across the peritoneal muscle layer, mesentery and the diaphragm was observed in MKN45/PAR1 and MKN74 cells which were pretreated with TFLLR-NH2 group (Figure 2C). The gene discussed is F2R; the disease is neoplasm.