In our previous study, using HIV-1 GAG-p24 in the model sPD1-p24fc/EP vaccine, we show that vaccine-elicited CD8+ T cells confer complete prevention and therapeutic cure of AB1-GAG malignant mesothelioma in immunocompetent BALB/c mice [5]. The gene discussed is HOXD13; the disease is malignant mesothelioma.