In ABCB1 deficient taxol-resistant A549 cancer cells, Cav-1 upregulation was observed [83] and Cav-1 overexpression correlated with little ABCB1 protein expression in human ovarian cancer cells, and ABCB1 overexpression was not localized in caveolae [98]. This evidence concerns the gene ABCB1 and ovarian carcinoma.