This study demonstrate that adiponectin, AdipoR1, leptin, Ob-R, COX-1, COX-2, aromatase, F2-isoprostanes, PGF2α metabolite and α-SMA are localised on higher levels in the breast tissues adjacent to the tumor compared to tumor specimens either on a score calculated from both the staining area and intensity or individually on the staining area or intensity of staining. This evidence concerns the gene ACTA1 and neoplasm.