ZNF217-mediated paclitaxel resistance in breast cancer cells was associated with alterations in the intrinsic mitochondrial apoptosis pathway, through the deregulation of the balance between anti-apoptotic (Bcl-2 and Bcl-XL) and pro-apoptotic (Bad, Bak and Bax) proteins' expression [28]. Here, BCL2L1 is linked to breast carcinoma.