Analyses of protein expressions in lysates of primary cells derived from patients with clinical lymphomas, albeit limited numbers (N = 41), reveal interesting sub-type specific associations, such as the strong correlation between, (a) STAT3pSer727 and total Bcl-2 expression in Large B cell Lymphomas, (b) Bcl-2pSer70 and total STAT3 levels in Diffuse Large B cell Lymphomas, (c) STAT3pTyr705 and Bcl-2pSer70 in Hodgkin's Lymphoma. The gene discussed is STAT3; the disease is diffuse large B-cell lymphoma.