CRP and atherosclerosis: CRP is a hepatically derived pentraxin, composed of five 23kDa subunits, and has a critical role in innate immune response.12 Hs-CRP has known as a marker for low grade systemic chronic inflammation, and is directly involved in the endothelial dysfunction, platelet aggregation and atherosclerosis.13 This protein has been shown to have prognostic value in patients with acute coronary syndromes (ACS) and plays different roles in pathogenesis of atherosclerosis.14 Indicators of these phenomena such as hs-CRP, MDA and VN would be associated with the risk of CAD.