The gene data sets 5-LOX activating protein (FLAP), 5-LOX, mPGES-1, mPGES-2, EGFR, and DclK1 were significantly decreased by the combination treatment during the progression of pancreatic lesions to ductal adenocarcinoma (Fig. 9C). The gene discussed is ALOX5; the disease is invasive ductal breast carcinoma.