URGCP and non-small cell lung carcinoma: Interestingly, the metastasis signal seemed to be largely emitted from lungs by ex vivo observation of the bioluminescent imaging of multiple organs, which was confirmed by the greatly increased number of lung metastatic nodules in mice injected with URGCP-overexpressing NSCLC cells compared to those injected with vector control cells (Fig. 4D–4F).