MYC and lung adenocarcinoma: Furthermore, a recent study showed that the MZF1 (Myeloid Zinc Finger 1)/c-MYC axis is essential for progression of lung adenocarcinomas; it is mediated by the cellular loss of the wild-type liver kinase B1 gene, i.e. a tumor suppressor frequently repressed in the pathogenesis of epithelial cancers [10].