Alike, among the 301 repressed genes 7% are known c-Myc targets or their relatives (Table 1, Figure 3A, right panel); nonetheless about half of the genes with increased expression in PLAC (56%) and the majority of down-regulated genes (79.4%) are so far unknown as c-Myc-targets in lung cancer. The gene discussed is MYC; the disease is lung carcinoma.