In HIV-1 infection, we find the following pseudogene:gene pairs with a positively correlated decrease in expression: ZNF137P:ZNF813, ANTXRLP1:ANTXRL, HNRNPA3P6:HNRNPA3/HNRNPA1, CTD-2008A1.2:SORD, KLHL2P1:BIRC5, KLHL2P1:TRIM59, KLHL2P1:MYB, RP11-114F3.5:TSEN2, RP11-114F3.5:SEPSECS, RP11-114F3.5:ZYG11B and RP11-490K7.4:ADAM10. The gene discussed is ZYG11B; the disease is HIV-1 infection.