LRG1 and lung carcinoma: Therefore the finding that LRG1 is elevated in lung cancer patients with poor response to radiotherapy indicates it may have three clinical uses: as a therapeutic target to increase the efficacy of radiotherapy, as a tool to stratify patients who require angiogenesis inhibitors in combination with radiotherapy (Wang et al., 2013) and as shown in this study as a biomarker for poor prognosis.