However, the bronchoscopic appearance easily differentiates it from TPO because amyloidosis involves the posterior aspect of the trachea with grayish submucosal plaques that bleed on contact.7 Sparing of the posterior (membranous) wall of the trachea has not been reported in cases of tracheobronchial amyloidosis, and in this case, was an important anatomical finding that allowed us to rule out amyloidosis. The gene discussed is TPO; the disease is amyloidosis.