TG and thyroid hormone resistance syndrome: The use of antithyroid medications in pediatric patients with RTH has been associated with goitrogenesis.3 From a pathophysiological standpoint, the use of methimazole or propylthiouracil in the patients with RTH may reduce the level of circulating thyroid hormones; however, it is unknown whether patients with RTH could derive any clinical benefits from the treatment with a thionomide.