TF and neoplasm: To the contrary, our patient had low levels of MVs exposing either PS or PS and TF compared to 209 patients with acute ischemic stroke without known malignancy, 205 × 106 MVs/L versus 1800 × 106 MVs/L.19 A possible explanation to the difference could be that MVs exposing TF are incorporated in the thrombi and “consumed”; a hypothesis supported by the highly hypercoagulative state and the rich staining of TF in both tumor and thrombi.