Similar to HPV infection, DEK expression is also differentially regulated during EBV infections [98]. DEK was one of three genes differentially regulated across two EBV+ tumor types and also differentially regulated between nasopharyngeal carcinoma cells with latent and recurrent EBV infections. DEK expression was downregulated in recurrent EBV-infected cells but upregulated in latent EBV-infected nasopharyngeal carcinoma (NPC) cells. Here, DEK is linked to Epstein-Barr virus infection.