WEE1 and melanoma: Lastly, assignment of 422 genes to InterPro domains (Supplementary Table S4) revealed that the top four categories represented in the dataset are: ‘Protein kinase, core’, ‘Protein kinase, ATP binding site’, ‘Tyrosine protein kinase’ and ‘Tyrosine protein kinase, active site’, thereby suggesting importance of kinase activity in melanoma cells.