Pathways playing important roles in the pathogenesis of melanoma are at the top enriched pathway list, such as ‘Pathways in cancer’, ‘Melanoma’, ‘Signaling by SCF-KIT’, ‘Oncogene Induced Senescence’, ‘p53 signaling pathway’, and ‘Downstream signal transduction’ (Supplementary Table S3). The gene discussed is KIT; the disease is melanoma.