TBL1XR1 and diffuse large B-cell lymphoma: Lymphoma risk SNPs are also enriched at binding sites of TBLR1 (p = 0.0005); disruptions at the TBLR1 locus in diffuse large B-cell lymphoma have been seen through a deletion of the locus [33] and the identification of a novel fusion between it and TP63, a paralogue of TP53 [34].