PSMB9 and classic Hodgkin lymphoma: In classical Hodgkin lymphoma (cHL), approximately 40% of cases are associated with EBV (EBV+cHL), and virus expression in the Hodgkin–Reed–Sternberg (HRS) cells is limited to the EBV nuclear antigen 1 (EBNA1) and latent membrane proteins (LMP1 and LMP2)1, 2, 3.