CDH17 and neoplasm: Serial studies have reported that theoverexpression of CDH17 in GC is associated with tumor node metastasis (TNM) and deeperinvasion, and it could be regarded as an independent prognostic marker inundifferentiated and stage II or III GC (11,12,16).However, other reports indicate that it participates in the development of GC so it maybe a promising prognostic marker for early-stage GC (15).