CCND1 and gastric cancer: The specific mechanisms by which CDH17 exerts a potential oncogenic role through theWnt/β-catenin pathway in GC include a decrease in the phosphorylation of glycogensynthase kinase-3β and β-catenin, together with a simultaneous increase ofretinoblastoma protein and decrease of cyclin D1, leading to an inhibition of cellproliferation (7).