NR4A1 and neoplasm: In both the tissue and cDNA arrays, TAGLN expression was downregulated in grade 3 tumors when compared to grade 1 and 2 tumors (P = 0.049 and P = 0.0329, respectively, Fig. 5c), upregulated in progesterone receptor PR (+) tumors (P = 0.0031 and P = 0.0043, respectively, Fig. 5d) and in any hormone receptor positive tumors with respect to triple negative tumor types (P = 0.0063 and P = 0.0489, respectively, Fig. 5e).