Furthermore, this is the first time an association between TAGLN expression and breast cancer prognosis is suggested by independent findings: (1) negative correlation of TAGLN expression with poor prognosis marker ANLN [40]; (2) decreased TAGLN expression particularly in triple negative breast cancer in addition to all molecular subtypes of breast cancer tissues; and (3) longer 10-year OS and RFS of low-grade breast cancer patients with higher TAGLN expression. The gene discussed is ANLN; the disease is breast cancer.