Furthermore, our previous studies demonstrated that KLF5 promoted cell proliferation, survival and tumour growth, partially through inducing the transcription of downstream target genes, such as fibroblast growth factor-binding protein 1 (FGF-BP)22, 23, 24 and microsomal prostaglandin E2 synthase 1 (mPGES1)25. Here, KLF5 is linked to neoplasm.