Deletion of HO-1 in myeloid cells (LyzM-Cre-Hmox1flfl) further significantly suppressed tumor growth as shown by Ki67 staining and growth curve evaluation (Figure 2C–2D, #p < 0.05, PC3+Hmox1flfl versus PC3+LyzM-Cre:Hmox1flfl). The gene discussed is HMOX1; the disease is neoplasm.