The results showed that the Glu-targeting coumarin liposomes or the functional coumarin liposomes were bound with the Glut-1 on the BMVECs, in contrast to the coumarin liposomes or cRGD-targeting coumarin liposomes (Fig. 3A), and that the cRGD-targeting coumarin liposomes or the functional targeting coumarin liposomes were bound to the integrin β3 receptors on the glioblastoma U251 cells, in contrast to the coumarin liposomes or Glu-targeting coumarin liposomes (Fig. 3B). This evidence concerns the gene SLC2A1 and glioblastoma.