PDGFB and meningioma: In PGDStv-a;RCAS-PDGF-B;AdCre;Nf2flox2/flox2mice the rate of meningioma development was significantly higher (15 of 29 mice; 52%) compared to AdCre;Nf2flox2/flox2 mice (4 of 25 age-paired mice; 16%; χ2, p = 0,02) (Table 1).