CRHR2 and anxiety disorder: We used as predictors the same covariates as in the previous analyses together with the PCA summary scores for each mitochondrial expression cluster and the normalized expression values for CRHR1, CRHR2 and NR3C1. The only association with the outcomes was found for CRHR1 that was positively associated with the MPSP index of State Anxiety together, as previously determined, with mitochondrial expression cluster 2 (S4 Table).