We have previously shown that IL-17A or Th2 cytokines also enhanced mucin (MUC) 5AC and MUC5B induction in NHBE cells [18–20], which causes the over production of mucus in chronic airway disorders such as chronic obstructive pulmonary disease (COPD) and asthma. The gene discussed is IL17A; the disease is chronic obstructive pulmonary disease.