TLR4 and cystic fibrosis: Concerning other TLRs, Mizunoe and colleagues [31] reported that IL-17A enhanced the production of IL-8 induced by peptidoglycan (TLR2 agonist) or lipopolysaccharide (TLR4 agonist) in bronchial epithelial cells from cystic fibrosis patients, but not in NHBE cells.