However, apocynin treatment reversed these abnormities after sepsis development [one-way ANOVA; CA1 (PV): F (3, 20) = 9.397, p < 0.01; CA3: F (3, 20) = 8.753, p < 0.01; CA1 (gp91phox): F (3, 20) = 6.227, p = 0.004; CA3 (gp91phox): F (3, 20) = 10.183, p < 0.01]. This evidence concerns the gene CYBB and Sepsis.