It is reported that miR-595 positively regulates ULK1 thereby inducing autophagy in SH-SY5Y cells, while miR-4487 negatively regulates ULK1 and thus inhibiting autophagy [129], which indicates that autophagy-modulating miRNAs in PD can be explored for potential PD therapeutic purpose. Here, ULK1 is linked to Parkinson disease.