In an effort to identify agents that suppress c-FLIP expression, we found that JQ1 at a range of 1 to 5 μM effectively decreased the levels of c-FLIP including both long (FLIPL) and short (FLIPS) forms in the 3 tested JQ1-senstive NSCLC cell lines, H157, H1299 and A549 (Figures. Here, CFLAR is linked to non-small cell lung carcinoma.