QBP1-HSC70bm peptides, which contain two mutant Huntingtin protein binding domain-polyglutamine binding peptide 1 (QBP1) domains and two HSC70 binding motifs (HSC70bm) reduced mutant Huntingtin protein aggregates and ameliorated the Huntington disease phenotype in a mouse model [176]. The gene discussed is HTT; the disease is juvenile Huntington disease.