Infusion of IL2 has been shown to increase Tregs in the circulation and in tissues of mice with LPS experimental nephrosis.[15, 16] Low-dose IL2 has also been successfully utilized in human beings with HCV-induced vasculitis[17] and in patients with Graft-versus-Host disease[18] to increase circulating Tregs and improving these conditions. This evidence concerns the gene IL2 and vasculitis.