Similar results were obtained for infiltrating cytotoxic T lymphocytes, with a higher number of CD8+ cells in tumor tissues compared with healthy controls [80 (69...93) vs. 17 (7...41)] and higher CD8+ cell infiltration in stage III vs. stage I lung cancer [132 (114...154) vs. 51 (27...98), Fig 4A and 4C]. This evidence concerns the gene CD8A and neoplasm.