CXCR4 has been reported as a prognostic biomarker in various type of cancer, including gastric cancer [36], colorectal cancer [37], esophageal cancer [38], pancreatic cancer [39], leukemia/lymphoma [40, 41], ovarian cancer [42] as well as breast cancer [3]. This evidence concerns the gene CXCR4 and familial pancreatic carcinoma.