Apart from classical TA repeat insertion, recent data have also shown that other common variants can contribute to mild hyperbilirubinemia in an additive manner with TA repeat, in particular rs4124874 and a coding SNP in UGT1A1 rs4148323 (G71R), with an influence on expression levels of UGT1A1 [8,9]. The gene discussed is UGT1A1; the disease is Hyperbilirubinemia.