The most meticulous of the studies in highly inflammatory conditions (active TB), Coussens et al,81 started with baseline CRP of 62.5 mg/L in the treatment group and it fell to 15.5 mg/L while the initial CRP in the placebo group was 62 mg/L initially and it fell to 19 mg/L after 8 weeks of anti-tubercular treatment (P ≤ 0.0072). Here, CRP is linked to tuberculosis.