In contrast, our highly novel observations that other benign vascular tumors such as adult capillary, cavernous, granulomatous, and venous hemangiomas as well as the single thrombophlebitis sample displayed expression of Oct4, Nanog, Myc, and Sox2 in similarly elevated rates and intensities as seen in malignant sarcomas was quite surprising. The gene discussed is POU5F1; the disease is sarcoma.