It was recently reported that benign infantile hemangiomas, which are the most common tumors of infancy, express higher levels of neural crest and stem cell markers at the mRNA level than dermal microvascular endothelial cells [10], and within this tumor type resides multiple cellular subpopulations expressing Oct4 and Nanog proteins [11]. This evidence concerns the gene POU5F1 and capillary hemangioma.