SNPs in the promoter of the KLK3 gene, encoding the commonly used PCa marker protein prostate‐specific antigen (PSA), were reported to increase serum PSA and PSA promoter activity [Cramer et al., 2003], whereas a C→ T substitution of SNP rs10993994:C>T in the 5′ region of the PCa‐suppressor gene MSMB was shown to affect gene expression level [Chang et al., 2009]. The gene discussed is PROS1; the disease is posterior cortical atrophy.