In this study, by coupling AR ChIP‐seq and microarray expression profiling of androgen‐regulated genes, we identified multiple AR regulatory elements (AREs) in the TMPRSS2‐ERG fusion gene‐positive DUCaP PCa cells and identified a novel auxiliary AR‐binding motif enriched in the vicinity of canonical androgen response elements. The gene discussed is ERG; the disease is posterior cortical atrophy.