ADRB2 and asthma: The Arg16Gly (rs1042713) and Gln27Glu (rs1042714)polymorphisms in the ADRB2 gene seem to be related to the developmentof overweight, hypertension, metabolic syndrome,9,10 and asthma exacerbations.11,12 They are associated with changes in thesympathetic nervous system activity and may alter lipolysis,9 metabolic and cardiovascular regulation,13 as well as decrease lung function and bronchodilator response totherapy with β2-agonists.14