PTEN and cancer: However, colon (HT-29 and colon-26), breast (MCF-7), and prostate (LNCaP, DU145, and PC-3) cancer cells were highly sensitive to MSE with the IC50 values of 39.37 ± 4.9 μg/mL (HT-29), 36.3 ± 4.9 μg/mL (colon-26), 37.3 ± 0.9 μg/mL (MCF-7), 34.26 ± 0.11 μg/mL (LNCaP), 39.38 ± 3.62 μg/mL (DU145), 38.26 ± 0.24 μg/mL (PC-3), and 35.91 ± 0.13 μg/mL (PTEN-CaP8) when compared with pancreatic cancer cells (Table1).