CRP and diabetes mellitus: There was, however, significant associations between sRAGE and age in the diabetes group (B = −51.5, R2 = 0.131 and p < 0.001, controlling for CRP), in boys with diabetes (B = −57.8, R2 = 0.071 and p = 0.004, no confounding variables) and in girls with diabetes (B = −45.5, R2 = 0.152 and p = 0.016, controlling for CRP).