The transcript for the protein myristolylated alanine-rich C-kinase substrate (Marcks) that is involved in altering the actin cytoskeleton [73], cell motility [74], and functions as a tumor suppressor [75] was originally shown to be downregulated in mouse 3T3 fibroblast cells expressing v-Src [76]. The gene discussed is MARCKS; the disease is neoplasm.