CD4 and neoplasm: T cell depletion in mice bearing SCC FAK-WT tumors (Figure 1D) revealed that: (1) depletion of CD8+ T cells, either alone or in combination with CD4+ T cells, caused a significant increase in tumor growth when compared to isotype-treated controls at day 14, and (2) depletion of CD4+ T cells alone caused regression of FAK-WT SCC tumors by day 21.