PEAR1 and diabetes mellitus: In our primary model accounting for clinical characteristics including age, sex, diabetes, SBP, DBP, and BMI, FMD was significantly higher in carriers of the PEAR1 rs12041331 A-allele when compared to subjects who did not carry this allele (GG = 10.2 ± 0.3, GA = 10.8 ± 0.6, AA = 16.5 ± 5.4, P = 0.019).