Our data provide new strong evidence that (i) fucose-rich epitopes of pBSDL-J28+, appearing during human pancreatic oncogenesis processes, are also expressed by murine PDAC cells Panc02; (ii) DC pulsed with the tumor pancreatic antigen skew adaptive immunity towards Th1 polarized responses; (iii) vaccination with C-ter-J28+ DC meets cancer vaccine objectives by inducing anti-Panc02 CD8+ T-cells and NK cells required to eradicate tumors and by promoting long-lasting resistance [23]. Here, CD8A is linked to cancer.