TP53 and ovarian carcinoma: Results of experiments with metastatic cisplatin-resistant human epithelial ovarian cancer xenografts established in nude mice and subjected to intraperitoneal chemotherapeutic treatment combining cisplatin (3 mg/kg) ± sodium arsenite (26 mg/kg) ± hyperthermia (37 or 43 °C) for 1 h revealed that cisplatin alone (±hyperthermia) induced TP53, XPC and XPA and suppressed MSH2 [50].