MTSS1 and hepatocellular carcinoma: MTSS1 (metastasis suppressor 1), a downstream target of DNMT3B, was found to function as a tumor suppressor in HCC by Fan et al. [25] In line with this finding, our study shows the repression of DNMT3B accompanied with elevation of MTSS1 by fucoidan inhibits growth and invasion activities of HCC cells.