In addition, we examined the biological effects of exposure to CdTe QDs in AML 12 cells to understand the CdTe QD induced cellular protective mechanism observed in AML 12 cells and clarify if Nrf2 or Nrf2-responsive genes could function as a possible sensitive marker for CdTe QDs-mediated toxicity in the liver. The gene discussed is NFE2L2; the disease is acute myeloid leukemia.